POXADOX

New polyoxazoline conjugates for cancer chemo-immunotherapy
Project ID: PN-III-P2-2.1-PED-2019-0745

Project Progress

Stage I/2020
Activity 1.1. Synthetic development of the precursor for DOX binding (CCO)

Stage II/2021
Activity 2.1. Synthetic development of the polymers (PiPOx) (CCO)
Activity 2.2. Synthetic development of PiPOx-DOX conjugates (CCO)
Activity 2.3 In vitro stability testing, drug release and cytotoxicity studies of materials (IC)
Activity 2.4 Interaction studies of PiPOx-DOX conjugates with tumor cells (IC)
Activity 2.5 Induction of ICD (IC)
Activity 2.6 Dissemination and participation in technical-scientific events (CCO and IC)